Search Results Image result for MALIGNANT HYPERTHERMIA Malignant hyperthermia (MH) is a disease that causes a fast rise in body temperature and severe muscle contractions when someone with the MH gets general anesthesia. Malignant Hyperethemia is passed down through families. Hyperthermia means high body
Observed during general anaesthesia.
Triggered by Succinylcoline, potent inhational anaesthetics extensive, glycosides & even caffeine!
Associated with rapidly rising temperature.
Most common in children, esp. with congenital abnormalities
Signs & symptoms:
· Unexplained tachycardia
· Increased production with tachypnoea
· Muscle rigidity
· Fever (late sign!).
1. GET THE “Malignant Hyperthemia BOX” & START MIXING DANTROLENE
2. Turn off all volatile anaesthetics & terminate surgery
3. Continuous monitoring
4. High dose
5. Check all observation (incl. saturations, end tidal core temperature)
6. IV access
7. FBC, U&E’s, LFT’s, Ca/P/ Mg, ABG’s
9. Catheterise as indicated
10. Initiate cooling, consider cool IV solutions, cool gastric or peritoneal lavage,
11. Dantrolene 2 mg/kg every 5 minutes up to 10 mg/kg,
Repeat every 6-8 hours for up to 3/7.